Which statement best describes Type D ADRs?

Which statement best describes Type D ADRs?

• A. They are dose-related
• B. They are immediate and common
• C. They are delayed, time related and often uncommon
• D. They are unpredictable immunological reactions

Answer: (C)

Type D adverse drug reactions are delayed effects that appear only after a substantial time has passed since exposure to the drug, and they can occur long after the drug has been used or even after withdrawal. They are characterized by a latent, time-related onset and are often uncommon. This distinguishes them from immediate, dose-related reactions or from unpredictable immunological reactions, which do not follow a predictable time course. Examples include late-onset carcinogenic or teratogenic effects or other effects with long latency.

Type D adverse drug reactions are delayed effects that appear only after a substantial time has passed since exposure to the drug, and they can occur long after the drug has been used or even after withdrawal. They are characterized by a latent, time-related onset and are often uncommon. This distinguishes them from immediate, dose-related reactions or from unpredictable immunological reactions, which do not follow a predictable time course. Examples include late-onset carcinogenic or teratogenic effects or other effects with long latency.