Which statement best describes inter-individual variability in drug response?

Which statement best describes inter-individual variability in drug response?

• A. Variation within the same individual over time.
• B. Variation between different individuals.
• C. Variation due to daily dosing schedules.
• D. Variation due to laboratory measurement error.

Answer: (C)

Inter-individual variability in drug response means differences in how different people respond to the same drug dose. This reflects genetic factors (like enzyme polymorphisms), age and organ function, body size, sex, disease states, other medications, and even adherence patterns. It contrasts with variation within the same person over time (intra-individual variability) or variability introduced by dosing regimens or measurement error. So the concept describes how diverse responses arise from differences between individuals, not from changes within the same person or from how the drug is dosed or measured.

Inter-individual variability in drug response means differences in how different people respond to the same drug dose. This reflects genetic factors (like enzyme polymorphisms), age and organ function, body size, sex, disease states, other medications, and even adherence patterns. It contrasts with variation within the same person over time (intra-individual variability) or variability introduced by dosing regimens or measurement error. So the concept describes how diverse responses arise from differences between individuals, not from changes within the same person or from how the drug is dosed or measured.